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Precis Future Med > Epub ahead of print
DOI: https://doi.org/10.23838/pfm.2021.00051    [Epub ahead of print]
Published online April 29, 2021.
Strategies for colorectal cancer screening and post-polypectomy surveillance for young adults under age 50
Yoon Suk Jung 
Division of Gastroenterology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea
Correspondence  Yoon Suk Jung ,Tel: +82-2-2001-8577, Email: ys810.jung@samsung.com
Submitted: March 24, 2021  Accepted after revision: April 3, 2021
Abstract
The incidence of colorectal cancer in young adults aged < 50 years is increasing. In line with these recent trends, it is necessary to pay attention to young-onset colorectal adenoma, a precursor of colorectal cancer. Recent studies have reported that the prevalence of colorectal adenomas in young adults aged < 50 years is not low. Moreover, it has been reported that the prevalence of advanced colorectal neoplasia (advanced adenoma or colorectal cancer) in young persons aged < 50 years with clinical risk factors or a positive fecal immunochemical test result is not lower than that in average-risk older persons. In this review, I examined and summarized the prevalence and risk factors of colorectal neoplasia (colorectal adenoma or colorectal cancer) in young adults aged < 50 years. Considering the results of previous studies, I proposed effective strategies for colorectal cancer screening using clinical risk factors and the fecal immunochemical test, and discussed post-polypectomy surveillance for this age group.
Keywords: Colorectal neoplasms; Young adults
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